The John B. Pierce Laboratory


  • Odors and flavors
    A special olfactometer delivers aromas to subjects in fMRI studies of how the human brain responds to odors and flavors
  • Sensing metabolic processes
    Molecular and immunohistochemical analyses are used to investigate how metabolic processes are sensed in the brain.
  • Sweet taste signals
    Labeling studies reveal neurons in the hippocampus that express glucose sensors similar to those that signal sweet taste on the tongue.
  • Thermal and chemical sensing
    Highly-controlled psychophysical studies translate advances in sensory neurobiology into new understanding of how humans sense their thermal and chemical environments.
  • Response to thermal environments
    Unique environmental chambers enable precise measurements of metabolic energy production in studies of how humans respond to their thermal environments.

Research Laboratories

The multidisciplinary approach of research at the Pierce Laboratory is reflected in the diversity of its individual research laboratories.

About Us

The John B. Pierce Laboratory was founded in 1933 and is a nonprofit, independent research institute affiliated with Yale University…

Our Staff

Find a complete listing of the Laboratory’s research, administrative, and support
staff here…

Our Mission

To conduct basic research on the interactions between physiological systems and the stresses imposed by the modern environment, with the goal of optimizing these interactions to improve human health and comfort.

Our Research

Scientists at the Laboratory study interactions with a variety of environmental stimuli and stressors at several different levels of analysis, ranging from molecular process within cells to behavioral processes of entire organisms…
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